When Is Yankees Opening Day 2025. Below are the matchups scheduled for that day: Traditional opening day, featuring 28 of the 30 major league clubs, will take place on thursday, march 27th.

Major league baseball unveiled the full schedule for 2025 regular season on thursday, and the yankees will open at home against the milwaukee brewers, with opening day set for thursday, march 27. Joe buck, the voice of espn’s monday night football and veteran of 24 world series, will call his first national major league baseball game since the 2021 world series on thursday, march.